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THUNDER Imaging Systems

The time has come for imaging systems that allow you to tackle easily biologically relevant 3D models: THUNDER Imagers.

To answer important scientific questions, they enable you to obtain a clear view of details, even deep within an intact sample, in real time without out-of-focus blur. Sharp imaging of 3D specimens is now as easy as working with your favorite camera-based fluorescence microscope. THUNDER Imagers with Computational Clearing define a new class of instruments for high-speed, high-quality imaging of thick, 3-dimensional specimens.

Decode 3D biology in real time*

THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay

THUNDER Imagers provide you with a solution for advanced 3D cell culture assays, whether you want to study stem cells, spheroids, or organoids.

Benefit from:

  • High throughput for better statistics and workflow efficiency
  • High imaging performance from an easy-to-use instrument
  • Optimal physiological conditions for meaningful results

THUNDER Imagers feature the innovative Leica technology Computational Clearing. It efficiently removes out-of-focus blur in real time, enabling the meaningful use of 3D specimens with camera-based fluorescence microscopes. The high sensitivity of the system ensures low phototoxicity and photobleaching, i.e., higher throughput with optimal conditions.

*in accordance with ISO/IEC 2382:2015

Decode 3D biology in real time*

THUNDER Imager Model Organism

The THUNDER Imager Model Organism allows fast and easy 3D exploration of whole organisms for developmental or molecular biology research. Thanks to Computational Clearing, your images reveal the finest structural details. No hassle with out-of-focus blur while maintaining the capabilities and ease-of-use typical for Leica stereo microscopes.

A THUNDER Imager Model Organism is the optimal instrument for studying, e.g., DrosophilaC. elegans, zebrafish, plants, and mice. One device for screening, positioning, and imaging your specimen. Simplify your workflow and study model organisms from a large overview to the highest detail.

Advantages for your research are:

  • Rapid acquisition of blur-free images showing fine details, even from deep within thick organisms
  • Keep even large model organisms under excellent physiological conditions during imaging
  • Simplify your organism handling for a more efficient imaging and analysis workflow

*in accordance with ISO/IEC 2382:2015

In-depth understanding of cellular structural biology

Cryo Light Microscope THUNDER Imager EM Cryo CLEM

The THUNDER Imager EM Cryo CLEM is a cryo light microscope featuring opto-digital THUNDER technology. It provides the imaging data and secure cryo conditions you need for successful experimental investigations concerning structural biology. Precisely identify cellular structures of interest thanks to high resolution, haze-free imaging with THUNDER technology, then transfer the specimen seamlessly to your EM.

Benefits include:

  • Fast, high-resolution imaging and elimination of out-of-focus blur with THUNDER technology 
  • Precise, seamless transfer of image data to different EM solutions
  • Optimal cryo conditions maintained throughout the imaging workflow and sample transfer

(For research use only)

THUNDER Imager Tissue

The THUNDER Imager Tissue allows real-time fluorescence imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur.

Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes.

Gain these advantages using a THUNDER Imager Tissue for your research:

  • Rapidly acquire blur-free images showing finest details of the morphology, even deep within thick sections

  • Get fast overviews of whole tissue sections

  • Image and analyze challenging tissue sections with an easy workflow

*in accordance with ISO/IEC 2382:2015

COVID-19 UPDATE: We are still fully operational for all microscope servicing and repairs. We are also still able to supply all microscopes and equipment as our supply chains for all products remain unaffected.

Contact for sales and servicing

Our friendly and knowledgeable staff are waiting to hear from you.

We will endeavour to assist you promptly with all Microscope related issues, including problems with 3rd party services and applications.

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